SOX2 and cancer: miRNA‐140‐5p has been demonstrated to play an important role in the initiation and progression of cancer, can inhibit tumor formation and metastasis of colorectal cancer and regulate the stem cells by suppressing the WNT, SOX2, and SOX9 (SRY‐Box Transcription Factor 2 and 9) stem cell regulator pathways in breast cancer (D. Wu, Zhang, et al., 2019).