PABPN1 and oculopharyngeal muscular dystrophy: The resulting Act88F-PABPN1-17alaR/+ individuals showed a stronger OPMD phenotype, namely more individuals had wing position defects than Act88F-PABPN1-17ala/+ (compare figure 4d and figure 5a), and importantly, they were not sensitive to oral treatment with 2 mM ICE (figure 5a).