Our findings indicate that SLC6A20 ishighly expressed in a variety of human tumor samples, and there isa positive correlation with SARS-CoV-2 infection genes, ACE2, TMPRSS2,and TMPRSS4, suggesting that SLC6A20 might be involvedin modulating COVID-19 disease and hence increased COVID-19 susceptibilityfor cancer patients. This evidence concerns the gene TMPRSS4 and neoplasm.