TheTIMER2.0 database25 was utilized for theassessment of co-expression of SLC6A20 with ACE2,TMPRSS2, and TMPRSS4 in TCGA pan-cancer samples and showed that amongthe gastrointestinal cancers, ESCA, PAAD, and STAD together with UCECand UCS exhibited positive correlation with SLC6A20 gene expression (Figure 4A). This evidence concerns the gene TMPRSS2 and cancer.