IL2 and Crohn disease: A predominantly anti-inflammatory effect was observed from clinical studies, where volunteers [healthy controls or patients with ulcerative colitis (UC) or Crohn’s disease (CD)] who took AndosanTM, showed a decrease in plasma levels of pro-inflammatory molecules (e.g., IL-1 β, IL-2, IL-5, IL-8, or calprotectin) [99–101].