Analysis of the immune status in mice by ELISA and flow cytometry revealed that: the level of anti-inflammatory cytokines in plasma, such as IL-10, IL-4, and TGFβ1, was increased after infusion; while pro-inflammatory cytokines, such as IFN-γ, IL-2, and IL-17, were downregulated, suggesting that MSCs can promote the shift of Th1 and Th17 cells to anti-inflammatory Th2 and suppressive Th3 cells in ITP mice. Here, IL4 is linked to autoimmune thrombocytopenic purpura.