Many factors, such as age, gender, smoking status, the plasma Epstein-Barr virus deoxyribonucleic acid (EBV DNA) status, serum lactate dehydrogenase (LDH) level and high-sensitivity C-reactive protein (hs-CRP) level, had been proved to affect the recurrence of NPC [28–30]. This evidence concerns the gene CRP and nasopharyngeal carcinoma.