Previous studies have reported that insufficient control of hyperthyroidism [2], high thyroid-stimulating hormones receptor antibody levels (TSH-R-Ab) [3], smoking [4, 5], radioactive iodine (RAI) treatment [6, 7], and high cholesterol levels [8, 9] are established risk factors for the development of GO in patients with GD. Here, TSHR is linked to geroderma osteodysplastica.