Genes positively correlated with purity showed enrichment in cancer-related pathways and processes such as epithelial-mesenchymal transition (BASP1, COL4A1, THBS2), genes involved in the TNFA signaling via NFKB (SPSB1, SMAD3), and genes upregulated by KRAS activation (CFB, MAFB). This evidence concerns the gene NFKB1 and cancer.