MCEMP1 and chronic asthma: To examine whether MCEMP1 deficiency impairs the immune response in chronic asthma model, 6–8 weeks old Mcemp1+/+ or Mcemp1–/– C57BL/6 mice were immunized via intraperitoneal injection of OVA on days 1, 4, and 7 (Fig. 5a).