Furthermore, DEGs of CD14 + CD163 high monocytes in patients with AIDP were significantly enriched in the cellular responders to interleukin- 1 and chemokine signaling pathways,indicating that CD14 + CD163 high monocytes may migrate out of blood vessels under the action of chemokines, and the IL1 signaling pathway may activate these monocytes during the AIDP inflammatory process. This evidence concerns the gene IL1B and Guillain-Barre syndrome, familial.