To determine the translational potential of FADS1, we used a FADS1 specific inhibitor, D5D-IN-326, to evaluate the anti-tumor effect in the orthotopic model, and the results showed that D5D-IN-326 treatment obviously inhibited the tumor growth and prolonged the overall survival of mice burdening with tumor (Fig. 7i, j). The gene discussed is FADS1; the disease is neoplasm.