Some of these include FOXC1 and FOXE3 in anterior segment dysgenesis syndrome type 3 and type 2, respectively, FOXF1 CNV, SNV, and lncRNA in lethal lung developmental defects, FOXG1 in an atypical Rett-like syndrome, FOXJ1 in one form of Ciliary Dyskinesia syndrome, FOXL2 in blepharophimosis-epicanthus inversus and ptosis syndrome, FOXE1 in the Bamforth-Lazarus syndrome, FOXP1 in intellectual disability with language impairment, FOXP2 in speech and language disorder, FOXN1 in T cell immunodeficiency, alopecia and nail dystrophy, and FOXP3 in immune regulation polyendocrinopathy syndrome34. The gene discussed is FOXP3; the disease is T-cell immunodeficiency.