However, in the breast cancer cells over-expressing ETV7, we could not observe this regulatory mechanism, even when STAT3 was activated by the treatment with IL-6 (Supplementary Fig. 4C), thus demonstrating that there is a putative competitive relationship between ETV7 and STAT3 in the regulation of the TNFRSF1A gene. This evidence concerns the gene TNFRSF1A and breast carcinoma.