Through lentivirus infection, the AS-circRNA that targets MET exon 13 could play functions in a range of cell lines, including HEK293T, HeLa, HepG2, U2OS, and HT-1080, indicating that AS-circRNAs have broad applicability to a variety of cell types (Fig. 1L). The gene discussed is MET; the disease is lentivirus infection.