PTBP2 and neuroblastoma: Although co-CM from PTBP2 overexpression group seldomly affect the cell cycle transition of SK-N-BE and SK-N-SH cells (Fig. S5B), CCK-8 and clone assays revealed that the proliferation of NB cells was significantly inhibited by co-CM from PTBP2-overexpressing group, while promoted by PTBP2 knockingdown co-CM, respectively (Fig. 3A and B).