In our study, we previously found that CD209+CD36+ monocytes were more abundant in mediastinal NB samples at advanced stages compared with earlier stages, while the CD80+CCR7+ subset abundantly existed in the early stage and demonstrated that classic monocytes were necessary for Mφ differentiation and infiltration, to sustain the inflammatory state in an early mediastinal NB environment. The gene discussed is CD36; the disease is neuroblastoma.