ITGB3 and colorectal carcinoma: First, we detected the expression level of ITGB3 through real-time quantitative polymerase chain reaction (RT-qPCR) in several CRC cell lines including SW620, SW480, HCT116, HT29, and Caco-2, in which Caco-2 and SW620 showed relatively high expression of ITGB3 (Fig. 5A).