Compared to the HC group, the exosome-associated expression of epidermal growth factor receptor pathway substrate 8, ITGB3, ITGA6, ADAM metallopeptidase domain 10 (ADAM10), integrin linked kinase, CD9, CD151, and ribosomal oxygenase 2 increased in plasma samples from CRC patients. The gene discussed is ILK; the disease is colorectal carcinoma.