Injection of higher nephritogenic doses (3×) of Cocktail D induced more albuminuria (Figure 1J) but also caused several-fold elevation of serum cardiac troponin I type 3 (cTPI3; myocardial injury, Figure 2A), serum alanine aminotransferase (ALT; acute liver injury, Figure 2B), serum creatinine (AKI, Figure 2C), and plasma creatine kinase (CK; skeletal muscle injury, Supplemental Figure 2A). Here, TNNI3 is linked to acute kidney injury.