Alternate avenues of research can potentially involve the measurement of vWF levels in patients with AS, then correlating vWF levels to colonoscopy findings (assessing for the presence of AVMs) and severity of LGIB and IDA (measured by hemoglobin and iron levels respectively). In addition, as it is known that aortic valve replacement is curative for Heyde's syndrome and significantly improves postoperative outcomes, comparing pre and post-AVR patients and associated outcomes is a potential area of study for such patients. Here, VWF is linked to aortic stenosis.