This finding suggests a strong impairment of neurological processes in hospitalized patients due to COVID-19, which builds on existing evidence.58, -60 Sleep disturbances have been associated previously with increased levels of inflammatory parameters IL-6 and CRP,61 also in our population of COVID-19 patients higher IL-6 and CRP concentrations in patients were related with neurological symptoms and sleep disturbance during acute infection. The gene discussed is CRP; the disease is COVID-19.