ATG4B and colorectal carcinoma: Furthermore, different demographic and clinicopathologic factors were analyzed among stratified factors such as sex, age, cell differentiation, etc. After assessing the clinical relevance of ATG4B and pATG4B protein expression level on the pathological stages and therapy with overall survival in patients with CRC, we proposed that ATG4B might serves as a biomarker for CRC, suggestive of a therapeutic target for the treatment of CRC.