CD34 and systemic lupus erythematosus: Abnormalities in immune cells in systemic lupus erythematosus (SLE) can also be traced to HSCs; the proliferation and differentiation of CD34 + cells in SLE patients are enhanced, the transcription of cytokines and chemokines is activated, and the activation of resting HSCs may aggravate the inflammation and attack risk of SLE [182].