HLA-DRB5 and Alzheimer disease: Similarly, in AD samples, we found 41 mQTLs, associated with DNA methylation at 9 significant CpGs (all of which are located in DMRs), overlapped with the LD regions chr 6:32,395,036–32,636,434 and chr 15:58,873,555–59,120,077, which included genetic variants mapped to HLA-DRA, HLA-DRB5, HLA-DRB1, HLA-DQA1, HLA-DQB1 on chromosome 6, and ADAM10, HSP90AB4P, LOC101928725, FAM63B on chromosome 15 (Supplementary Table 14).