The maximum VAF of somatic mutations of genes (AHNAK2, TTN, MUC17, MUC16, MAGEC1, FAM47C, MACF1, RPL1, FLG, PCLO, and ZNF208) in tumor tissues was positively correlated with that in cfDNA (Cor = 0.759; R2 = 0.576; p = 2.65 × 10–21, Fig. 6B). The gene discussed is ZNF208; the disease is neoplasm.