The results suggested that high ZDHHC3/4/7/9/15/17/20/22 expression in pancreatic cancer is closely related to patients’ individual cancer stages, and advanced cancer patients were more inclined to express higher mRNA expression of ZDHHC3/4/7/9/15/17/20/22 (all P < 0.05) (Additional file 1: Fig. S2), and other ZDHHCs show no significant difference (Additional file 1: Fig. S3). Here, ZDHHC3 is linked to cancer.