Similarly, other chemokines, including CCL2, CCL3, CCL8, CCL11, CCL12, CCL14, CCL16, CCL19, CCL21, and CCL23, and paired receptors including CCR1, CCR2, CCR4, CCR5, CCR6, CCR7, CXCR1, and CXCR6, were found to be negatively correlated with ZDHHC3 expression in PAAD (Fig. 4A; Additional file 1: Fig. S8). This evidence concerns the gene CCL16 and pancreatic adenocarcinoma.