Dysregulation of SOX2 expression has been linked to cancer pathogenesis through its role in induction of cellular proliferation mediated by epidermal growth factor receptor (EGFR) activation, epithelial-to-mesenchymal transition (EMT), and resistance to apoptosis mediated by B-cell lymphoma 2 like1 (BCL2L1) induced survival signaling [16]. This evidence concerns the gene EGFR and cancer.