In support of the notion that OTUD6B enhances β‐TrCP protein stability and thus decreases SNAIL protein level, we found a significant positive correlation between OTUD6B and β‐TrCP protein levels in ESCC tissues (Figure 5C) and a negative correlation between OTUD6B and SNAIL protein levels (Figure 5D). Here, OTUD6B is linked to esophageal squamous cell carcinoma.