BTRC and cancer: However, at the protein level, β‐TrCP expressed at lower level in ESCC tissues than in adjacent normal tissues (Figure 1B,C), which is consistent with a previous report.[8] The clinical proteomic tumor analysis consortium (CPTAC) data also suggest that decreased protein level of β‐TrCP exists in other cancer types, including breast invasive carcinoma, colon adenocarcinoma, and glioblastoma (GBM) (Figure S1A, Supporting Information).