Additionally, 55 genes with in the T‐1 and T‐2 gene tracks similarly and significantly upregulated in fibrotic lungs of mice and two independent human IPF cohorts (Figure 7D).Furthermore, we note that the clinical significance of these pathways associated with T‐1 and T2 have previously been described.[18–21] Furthermore, some of these pathways, such as PI3K‐Akt signaling pathways[22] and ECM‐receptor interaction,[23] have been studied in clinical trials, providing successful outcomes at certain endpoints. The gene discussed is AKT1; the disease is idiopathic pulmonary fibrosis.