Moreover, ST’s infection (MOI 100:1 CFU/cells) caused the up-regulation of IL6 (P < 0.000 1), CXCL8 (P < 0.0001) and IL15 (P < 0.0001) expression 1 h post-infection, while MYD88 (P = 0.0242), NFKB/p65 (P = 0.0414), RAD51 (P = 0.0002) and TP53 (P = 0.0012) were down-regulated (Fig. 4). The gene discussed is NFKB1; the disease is infection.