INS and type 1 diabetes mellitus: Participants (58% women) had a mean age of 47 (SD 15) years, duration of type 1 diabetes of 27 (SD 13) years, BMI of 28.3 (SD 4.2) kg/m2, total daily insulin dose of 45 (SD 20) U and HbA1c level of 56 (SD 6) mmol/mol (7.3% [SD 0.5]).