HOXB8 and Anxiety: The latter results corroborate the results we obtained with the elevated plus maze tests in terms of anxiety as measured by reduced time spent exploring the central domain in OFTs (Fig. 3f–g; Supplementary Fig. 7m, n) as well as in increased freezing time in periphery (Fig. 3h, i; Supplementary Fig. 7b BLA, 7f CeA Hoxb8; 7d C57bl/6 BLA, 7h CeA C57bl/6).