In a study on mice inoculated with the same cell line as in the present study, using of cationic liposomes with gp10025-33 self-antigen and comparsion with its free form showed a favorable tumor regression for the liposomal form40, which confirms the general results of the present study, considering the effectiveness of Lip-gp100 as a vaccine for melanoma. This evidence concerns the gene PMEL and neoplasm.