Six young female cFD (36 ± 10 years) had normal septal T1 values > 996 ms with minimally increased Lyso-Gb3 of 2.2 ± 1.1 (norm: < 0.9 ng/ml), normal other blood sample results (Troponin T < 14 pg/mL, NT-proBNP < 125 pg/ml), without left ventricular hypertrophy (LVH-), diastolic dysfunction (E/A > 2), atrial fibrillation or myocardial fibrosis (LGE-). The gene discussed is NPPB; the disease is Myocardial fibrosis.