IFNAR1 and viral infectious disease: Although we detected a similar viral load in cerebral cortex of WT and Ifnar–/– mice at endpoint (Supplementary Fig. 4c), the response to viral infection was markedly different in WT and Ifnar–/–, and a lower number of DEGs were identified (1,039) in Ifnar–/– (Fig. 5f, g, Supplementary Data 2).