Administration of adenoviral vector constructs did not result in significant reduction in weight loss at days post infection (DPI) = 7 and 8 compared when with the Ad-empty negative control, this includes Ad-01G, Ad-01 fusion + Ad-GroEL, and Ad-CBU0091 + Ad-CBU1652 + Ad-GroEL. Here, HSPD1 is linked to infection.