Furthermore, the results in Fig 3C and 3D, demonstrate that ADAR1 expression is upregulated in ischemic and dilated cardiomyopathies compared to controls (Wilcoxon rank-sum test, p-value = 0.00002, 0.000003 in dilated and ischemic cardiomyopathies, respectively), with no change in the other cohorts. This evidence concerns the gene ADAR and dilated cardiomyopathy.