ADAR and cardiomyopathy: Moreover, we observed a positive linear relationship between ADAR1 expression, and the Alu editing and ISG scores in cardiomyopathies samples, which implicates RNA editing in these conditions, and these three parameters exhibit positive pairwise correlations (Spearman, rho = 0.48, 0.58 and 0.45; p-value = 1.5e-06, 1.2e-09 and 5.9e-06, for ADAR1 expression vs. ISG score, ADAR1 vs. Alu editing and Alu editing vs. ISG, respectively).