GRIA2 and hepatocellular carcinoma: For example, recoding of the Q/R site within the Glutamate ionotropic receptor AMPA type subunit 2 (GRIA2) gene is essential to prevent an inborn fatal phenotype in mice [3,4], and editing of the Antizyme inhibitor 1 (AZIN1) site induces an S/G change, which drives the development of hepatocellular carcinoma [5].