However, we did not find a significant association between CLOCK polymorphisms and breast cancer [dominant model: OR (95%CI) = 0.98 (0.91, 1.04), Fig. 2; over-dominant model: OR (95%CI) = 1.00 (0.96, 1.05), Fig. 3; recessive model: OR (95%CI) = 0.98 (0.94, 1.03), Fig. 4]. The gene discussed is CLOCK; the disease is breast cancer.