In addition, melanoma patients were also divided into four subtypes based on some mutated genes, and they were B-Raf Proto-Oncogene, Serine/Threonine Kinase (BRAF) hotspot, RAS hotspot, Neurofibromin 1 (NF1) mutant, and Triple-WT (wild-type) [29]. Here, MARK2 is linked to melanoma.