Expression of NF-kB associated or mediated inflammatory factors that have been found to increase or contribute to dry eye pathogenesis, including myd88, cytokines il12a, il12b (a subunit shared by IL-23 and IL-12), ltb and chemokine ccl2, was evaluated by PCR.11 The gene discussed is NFKB1; the disease is Keratoconjunctivitis sicca.