We found that GS‐II‐HRP staining of the luminal surface of colorectal cancer cells was partially attenuated by PNGase F digestion, although that staining did not completely disappear, unlike our previous observations seen in colorectal carcinoma tissue lysates13, 14, 25 (see Figure 3g,h). The gene discussed is NGLY1; the disease is colorectal carcinoma.