In serrated pathway‐associated colorectal carcinogenesis, lesions bearing activating BRAF mutations develop into MVHPs, further develop into SSLs as promoter regions of several genes become methylated, and finally develop into MSI‐H and CIMP‐H colorectal carcinomas once hMLH1 is inactivated by methylation of the promoter region.6 Here, MLH1 is linked to colorectal carcinoma.