GSN and cancer: In paired samples from 18 malignancies, we discovered that GSN mRNA expression patterns were elevated significantly in malignancies such as CHOL, KIRC and LIHC compared to neighboring normal tissues and significantly downregulated in cancers: BLCA, BRCA, COAD, HNSC, KICH, KIRP, LUAD, LUSC, PRAD, READ, STAD and UCEC (p < 0.05; Figure 1C).