In contrast, P4HA3 was expressed at lower levels than normal tissues in eight tumors, including liver hepatocellular carcinoma (LIHC), ovarian serous cystadenocarcinoma (OV), skin cutaneous melanoma (SKCM), thyroid carcinoma (THCA), uterine corpus endometrial carcinoma (UCEC), bladder urothelial carcinoma (BLCA), brain lower grade glioma (LGG), and testicular germ cell tumors (TGCT) (Figure 1D). This evidence concerns the gene P4HA3 and cutaneous melanoma.