Viral-delivered gene therapies have been explored preclinically for most forms of Batten disease (Johnson et al., 2019a), and clinically for CLN2, CLN3, CLN5, CLN6, and CLN7, with results pending (NCT#s: 01161576, 00151216, 01414985, 03770572, 04273243, 05228145, 04737460). Here, CLN3 is linked to juvenile neuronal ceroid lipofuscinosis.