CYP19A1 and benign prostatic hyperplasia: Abnormal in-utero programing of steroidogenic enzyme activity, particularly aromatase, the rate-limiting enzyme in the conversion of androgens to estrogens, is speculated in preeclamptic offspring, and may also occur in the BPH/5 mouse model (Mouritsen et al., 2015; Alsnes et al., 2016; Berkane et al., 2018; Noyola-Martinez et al., 2019).