Furthermore, loss of function mutations in ZDHHC9 result in X-linked intellectual disability (XLID), with affected individuals displaying neurodevelopmental delay, seizures, and facial dysmorphism (Raymond et al., 2007; Baker et al., 2015; Han et al., 2017; Schirwani et al., 2018). This evidence concerns the gene ZDHHC9 and cask-related x-linked intellectual disability.