Further genomic characterization of canine rhabdomyosarcoma is needed to determine if the molecular pathogenesis of these tumors is similar to their human counterparts, with particular attention to the presence of PAX3/7-FHKR gene fusions, which are a hallmark of the more aggressive alveolar rhabdomyosarcoma subclass in people and have both diagnostic and prognostic utility (109–111). This evidence concerns the gene PAX3 and rhabdomyosarcoma.