DDX3X and B-cell non-Hodgkin lymphoma: Because mouse models in which one or two alleles of DDX3X can be deleted do not reproduce the phenotype seen with human B cells that have acquired mutations leading to a partial LOF or a dominant negative allele, further experiments with mice that harbor conditional knock-in alleles allowing expression of human DDX3X mutant alleles could be informative as to why DDX3X/Y requirement for B-cell lymphoma diverge between mice and humans.