explored the association of cuproptosis related genes with skin cutaneous melanoma (SKCM) prognosis by accessing and analyzing a public database, and found that 11 out 12 genes were upregulated in melanoma tissues and three genes (LIPT1, PDHA1, and SLC31A1) were of predictive value for melanoma prognosis. This evidence concerns the gene PDHA1 and melanoma.