In recent times, several documents suggest that both CD4+ and CD8+ T cells are involved in COVID‐19‐mediated ischemic brain injury where self‐reactive T cells can attack the brain tissues due to cytokine response resulting in a reduced number of monocytes, upregulation of the components of anti‐inflammatory circuits, impairment of some effector proteins leading to long term damage of the brain and ultimately cause the death of the patients.13, 14. Here, CD8A is linked to COVID-19.