IL1B and COVID-19: It was also reported that virus titers in COVID‐19 patients are significantly higher in the case of TLR3 that recruits a high amount of adapter‐inducing interferon‐b (TRIF) in the TIR‐domain of the adaptor molecules leading to high IL‐6 and IL‐1beta production in immunocompromised mice in comparing to their wild‐type counterparts leading to severe lung damage.151