CD274 and cancer: The enrichment results of the KEGG pathway are shown in Figure 1(d), involving 30 pathways, mainly including lipid and atherosclerosis, autophagy—animal, mitophagy—animal, programmed cell death 1 ligand 1 (PD-L1) expression and PD-1 checkpoint pathway in cancer, pathways of neurodegeneration—multiple diseases, etc. The KEGG enrichment analysis conducted by GSEA shows that it mainly involves focal adhesion, DNA replication, proteasome, oocyte meiosis, toll-like receptor signaling pathway, cell cycle (Figure 1(e)).