In silico comparative genomic mapping with additional 14 CNVs in this genomic region identified one potential KS candidate gene (TSPAN11), seven candidate genes for neurodevelopmental disorder (TM7SF3, STK38L, ARNTL2, ERGIC2, TMTC1, DENND5B, and ETFBKMT) and four candidate genes for KS with ID (INTS13, REP15, PPFIBP1, and FAR2). The gene discussed is DENND5B; the disease is neurodevelopmental disorder.