Some lysine methyltransferases such as KMT2C (Lysine Methyltransferase 2C, MIM 606833, aka MLL3), SETD1B (SET Domain Containing 1B, MIM 611055, aka KMT2G, Lysine-specific Methyltransferase 2G)23,86, EHMT1 (Euchromatin Histone Lysine Methyltransferase 1, MIM 607001)87,88, and KMT5B (Lysine Methyltransferase 5B, MIM 610881)89 are well known to be associated with neurodevelopmental disorders. This evidence concerns the gene SETD1B and neurodevelopmental disorder.