ERGIC2 physically interacts with SLC39A8 (Solute Carrier Family 39, Member 8, MIM 608732)55,59 and CUX1 (Cut-Like Homeobox, 116896)60, which are associated with autosomal recessive syndromic intellectual disability61 and non-syndromic intellectual disability/development delay62, respectively. The gene discussed is SLC39A8; the disease is Intellectual disability.